Cymbalta is an antidepressant approved to treat mood and pain disorders. It was one of Eli Lilly’s most profitable drugs. It works by preventing the body from reabsorbing two neurotransmitters: serotonin and norepinephrine. Earle & Company, est. 2017, is a nimble and highly-skilled expeditionary force for innovation. Whether the need is a design idea or anything else on the creative spectrum, R&D tech activation via our proprietary MIND INTO MATTER™ process, training and events to help people become more creative themselves, innovation strategy, or a venture. Cymbalta, or Duloxetine is a serotonin-norepinephrine reuptake inhibitor used to treat depression and neurological pain. Find out about the uses and risks. Cymbalta ® is indicated for the treatment of: Major Depressive Disorder [see Clinical Studies ] Generalized Anxiety Disorder [see Clinical Studies ] Diabetic Peripheral Neuropathy [see Clinical Studies ] Fibromyalgia [see Clinical Studies ] Chronic Musculoskeletal Pain [see Clinical Studies ] Cymbalta Dosage and Administration Learn about Cymbalta (Duloxetine Hcl) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Nausea, headache and a dry mouth are among the most common side effects of Cymbalta. In rare cases, patients have suffered serious — and sometimes fatal — side effects, including liver damage, abnormal bleeding, and suicidal thoughts and behaviors. Cymbalta increases the action of serotonin and norepinephrine, which are natural neurotransmitters produced by the body. This effect of Cymbalta alleviates depression and anxiety and decrease pain signals in the brain, spinal cord, and nerves. Cymbalta (duloxetine), a drug prescribed for neuropathic pain associated with diabetic peripheral neuropathy, depression, and anxiety. Side effect, dosage, and drug interaction information included. Cymbalta Side Effects: An Introduction As with any medicine, there are possible side effects with Cymbalta ® (duloxetine hydrochloride). However, not everyone who takes Cymbalta will experience side effects. Cymbalta (generic name duloxetine) is an SNRI-type antidepressant commonly used to treat major depressive disorder, generalized anxiety disorders, neuropathic pain and fibromyalgia.